3 Akero employees smiling and conversing in a communal space

Our Company

We are passionate about developing novel therapies for patients with serious metabolic diseases that lack effective treatment options.

Akero is a clinical-stage company founded to develop transformational treatments for patients with serious metabolic diseases marked by high unmet medical need.

We began with an engineered protein called efruxifermin (EFX), which we licensed from Amgen and are developing for the treatment of metabolic dysfunction-associated steatohepatitis (MASH). MASH is a serious liver disease caused by metabolic dysregulation for which there are limited treatment options. We believe restoring whole-body metabolic balance is the key to addressing metabolic dysregulation and bringing impactful therapeutic options to patients—and we believe EFX is ideally suited for this challenge.

“Where we’re able to develop a compound that can treat the person as a whole—that’s the holy grail, and that’s the target of what we’re trying to do in drug development for MASH.”

–Stephen Harrison, M.D.
Medical Director, Pinnacle Clinical Research

Educational video about metabolic dysfunction-associated steatohepatitis (MASH) and EFX
Close-up shot of Akero employee talking about data displayed on a computer screen

We have achieved a number of milestones in our quest to bring novel therapies to patients.