Publications & posters Our drug R&D is supported by scientific research published by the Akero team, our collaborators, and by external experts. Filter View all EFX FGF21 MASH Nov 2014 | FROM EXTERNAL EXPERTS Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets Fisher, F.M. et al. Gastroenterology Nov 2009 | FROM EXTERNAL EXPERTS Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models–association with liver and adipose tissue effects Xu, J. et al. American Journal of Physiology. Endocrinology and Metabolism Feb 2007 | FROM EXTERNAL EXPERTS The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21 Kharitonenkov, A. et al. Endocrinology Page 8 of 8« First<<...45678 We have developed a comprehensive clinical program to evaluate EFX as a potential treatment for MASH. View Our Pipeline